Variable-field relaxometry of iron-containing human tissues: a preliminary study.

  title={Variable-field relaxometry of iron-containing human tissues: a preliminary study.},
  author={Aline Hocq and Nicolas Brouette and Sven Saussez and Michel Luhmer and Pierre Gillis and Yves Gossuin},
  journal={Contrast media & molecular imaging},
  volume={4 4},
Excess iron is found in brain nuclei from neurodegenerative patients (with Parkinson's, Alzheimer's and Huntington's diseases) and also in the liver and spleen of cirrhosis, hemochromatosis and thalassaemia patients. Ferritin, the iron-storing protein of mammals, is known to darken T(2)-weighted MR images. Understanding NMR tissue behavior may make it possible to detect those diseases, to follow their evolution and finally to establish a protocol for non-invasive measurement of an organ's iron… CONTINUE READING


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