Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of premenopausal women.

@article{Losordo1994VariableEO,
  title={Variable expression of the estrogen receptor in normal and atherosclerotic coronary arteries of premenopausal women.},
  author={Douglas W. Losordo and Michael Wayne Kearney and Eon A Kim and J Jekanowski and Jeffrey M. Isner},
  journal={Circulation},
  year={1994},
  volume={89 4},
  pages={1501-10}
}
BACKGROUND The relative absence of coronary atherosclerosis in premenopausal women has been established. Estrogen is presumed to play a role in the protection of coronary arteries from atherosclerosis, and part of this protective effect appears to be mediated by amelioration of serum lipid profiles. However, all of the atheroprotective effect of estrogen is not explained by alteration of serum lipids. In this study, we attempt to identify evidence of estrogen receptors in coronary artery… CONTINUE READING