Variable expression of cytokines in human head and neck squamous cell carcinoma cell lines and consistent expression in surgical specimens.

@article{Woods1998VariableEO,
  title={Variable expression of cytokines in human head and neck squamous cell carcinoma cell lines and consistent expression in surgical specimens.},
  author={Kandy Woods and A El-naggar and Gary L Clayman and Elizabeth Ann Grimm},
  journal={Cancer research},
  year={1998},
  volume={58 14},
  pages={3132-41}
}
Head and neck squamous cell carcinomas (HNSCCs) are associated with abnormal cell-mediated immunity at the primary tumor site. We investigated tumor-derived cytokines as factors underlying such abnormalities. Cytokine mRNA and protein of eight HNSCC-derived cell lines were tested; reverse transcription-PCR results indicated the presence of mRNAs for interleukin 1alpha (IL-1alpha) and transforming growth factor alpha (8 of 8); transforming growth factor beta and IL-1beta (7 of 8); and IL-4 and… CONTINUE READING

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We investigated tumor - derived cytokines as factors underlying such abnormalities .
We investigated tumor - derived cytokines as factors underlying such abnormalities .
Cytokine mRNA and protein of eight HNSCC - derived cell lines were tested ; reverse transcription - PCR results indicated the presence of mRNAs for interleukin 1alpha ( IL-1alpha ) and transforming growth factor alpha ( 8 of 8) ; transforming growth factor beta and IL-1beta ( 7 of 8) ; and IL-4 and IL-6 ( 4 of 8) .
Cytokine mRNA and protein of eight HNSCC - derived cell lines were tested ; reverse transcription - PCR results indicated the presence of mRNAs for interleukin 1alpha ( IL-1alpha ) and transforming growth factor alpha ( 8 of 8) ; transforming growth factor beta and IL-1beta ( 7 of 8) ; and IL-4 and IL-6 ( 4 of 8) .
Cytokine mRNA and protein of eight HNSCC - derived cell lines were tested ; reverse transcription - PCR results indicated the presence of mRNAs for interleukin 1alpha ( IL-1alpha ) and transforming growth factor alpha ( 8 of 8) ; transforming growth factor beta and IL-1beta ( 7 of 8) ; and IL-4 and IL-6 ( 4 of 8) .
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