Variable J‐chain content in human IgM

@article{Mihaesco1973VariableJC,
  title={Variable J‐chain content in human IgM},
  author={C. Mihaesco and E. Mihaesco and H. Metzger},
  journal={FEBS Letters},
  year={1973},
  volume={37}
}
Human IgM consists of 10 heavy '/a' chains and 10 light-chains interlinked by disulfide bridges and organized in 5 subunits (IgM's) each containing 2 '/l'and 2 light-chains. An additional polypeptide fragment, designated J-chain, has been found associated with polymeric immunoglobulins IgA and IgM [ 1, 2]. The structure of J-chain appears to be unrelated either to immunoglobulin 'homology' regions or to the 'secretory piece' which is associated with secretory IgA [37]. The present study was… Expand
22 Citations
IgM reassociation in the absence of J-chain.
Structural and functional analysis of J chain-deficient IgM.
Interplay of J chain and disulfide bonding in assembly of polymeric IgM.
Immunochemical Studies on Free and Bound J Chain of Human IgA and IgM
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Binding of secretory component to human immunoglobulin M.
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