Variable Effects of Autophagy Induction by Trehalose on Herpesviruses Depending on Conditions of Infection

Trehalose is a non-reducing sugar formed from two glucose units. Trehalose induces abundant autophagy in cultured cells and also reduces the rate of aggregation of the huntingtin protein in the animal model of Huntington disease, a chronic neurological disease in humans. The mechanism of this effect on autophagy is now known to be caused by starvation… CONTINUE READING