Variable Diastolic Ventricular Compliance : a General Property of Mammalian Cardiac Muscle

@article{Scherlag1966VariableDV,
  title={Variable Diastolic Ventricular Compliance : a General Property of Mammalian Cardiac Muscle},
  author={Benjamin J. Scherlag and H. J. Bartelstone and S R Wyte and Brian F. Hoffman},
  journal={Nature},
  year={1966},
  volume={209},
  pages={1246-1248}
}
STUDIES of the extensibility of quiescent cardiac muscle have been the cause of recurrent controversy. Starling's law of the heart relates the energy of contraction to the length the muscle fibres attain just prior to contraction. In studies of the regulation of cardiac contraction the assumption is made that measurement of pressure within the ventricle during diastole provides an accurate index of ventricular volume and that changes in pressure thus predict changes in fibre length1. This… CONTINUE READING

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