Variability of plasma apolipoprotein (apo) A-II levels associated with an apo A-II gene polymorphism in monozygotic twin pairs.

@article{Thorn1993VariabilityOP,
  title={Variability of plasma apolipoprotein (apo) A-II levels associated with an apo A-II gene polymorphism in monozygotic twin pairs.},
  author={J A Thorn and J. Stocks and Dr. Carl Reichl and Juan C. Alcolado and J C Chamberlain and D. J. Galton},
  journal={Biochimica et biophysica acta},
  year={1993},
  volume={1180 3},
  pages={299-303}
}
A dimorphic MspI RFLP (alleles M1 and M2) in an Alu unit 528 base pairs downstream from the apolipoprotein A-II gene on chromosome 1 was investigated for associations with dyslipoproteinaemia or coronary atherosclerosis. No significant differences were observed between the allele frequencies in healthy random controls (M2 = 0.850, n = 70) and patients with primary hypertriglyceridaemia (M2 = 0.846, n = 52) or severe coronary atherosclerosis (M2 = 0.819, n = 47). The apolipoprotein A-II gene may… CONTINUE READING

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