Variability of cortical evoked potentials to tooth pulp stimulation in unrestrained rats

Abstract

In unrestrained adult rats evoked potentials were recorded by implanted electrodes in the somatosensory cortex in response to electrical stimulation of the pulp of an upper incisor. The spontaneous EEG, motor activity of the animal, and its respiratory movements were recorded simultaneously. Significant differences were observed in the configuration of the potentials and mean amplitude of the primary complex (P1+N1) during states of slow sleep, drowsiness, relaxed wakefulness, grooming, and investigative behavior; the amplitude of the primary complex during marked motor activity was reduced by more than an order of magnitude compared with that observed in a state of motor rest. In a state of relaxed wakefulness negative correlation was recorded between the amplitude of evoked potentials and momentary values of the respiration rate, weaker during periods of intensive motor activity. Meanwhile no direct parallel was observed between changes in potentials and respiration rate over the whole range of behavioral states studied: Depression of potentials was maximal during grooming whereas the respiration rate was maximal during investigative behavior.

DOI: 10.1007/BF01052787

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Cite this paper

@article{Rehnig2005VariabilityOC, title={Variability of cortical evoked potentials to tooth pulp stimulation in unrestrained rats}, author={H. -P. Rehnig and J. Brankatschk and Fritz Klingberg}, journal={Neurophysiology}, year={2005}, volume={17}, pages={23-29} }