Variability of colonic function in healthy subjects.

  title={Variability of colonic function in healthy subjects.},
  author={J B Wyman and Kenneth W. Heaton and Adrian P Manning and Antony C Wicks},
  volume={19 2},
Twenty healthy subjects eating normal diets made repeated five-day stool collections, the 10 females making their collections in four to six successive weeks. In most subjects there were striking variations in transit time, measured by Hinton's method. The variability of average faecal wet and dry weight, faecal volume, and the frequency of defaecation was equally great, suggesting that the transit time variations were genuine. The size of individual stools varied even more, often tenfold or… CONTINUE READING


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