Variability of chromosome structure in pathogenic fungi--of 'ends and odds'.

  title={Variability of chromosome structure in pathogenic fungi--of 'ends and odds'.},
  author={Jonathan M. Galazka and Michael Freitag},
  journal={Current opinion in microbiology},
Chromatin structure can affect the organization and maintenance of chromosomes. Recent discoveries in several filamentous fungi suggest mechanisms for the clustering and co-regulation of secondary metabolite genes or pathogenicity islands. An extreme case of this may be fungal 'accessory', 'conditionally dispensable', or 'supernumerary' chromosomes that often confer beneficial traits. Fungal supernumerary chromosomes may be derived by similar mechanisms as animal or plant B chromosomes, and we… CONTINUE READING
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