Variability of Organophosphorous Pesticide Metabolite Levels in Spot and 24-hr Urine Samples Collected from Young Children during 1 Week

@inproceedings{Bradman2013VariabilityOO,
  title={Variability of Organophosphorous Pesticide Metabolite Levels in Spot and 24-hr Urine Samples Collected from Young Children during 1 Week},
  author={A S A Bradman and Katherine R. Kogut and Ellen A. Eisen and Nicholas Patrick Jewell and Lesliam Quir{\'o}s-Alcal{\'a} and Rosemary Castorina and Jonathan Chevrier and Nina Titenko Holland and Dana Boyd Barr and Geri Kavanagh-Baird and Brenda Eskenazi},
  booktitle={Environmental health perspectives},
  year={2013}
}
BACKGROUND Dialkyl phosphate (DAP) metabolites in spot urine samples are frequently used to characterize children's exposures to organophosphorous (OP) pesticides. However, variable exposure and short biological half-lives of OP pesticides could result in highly variable measurements, leading to exposure misclassification. OBJECTIVE We examined within- and between-child variability in DAP metabolites in urine samples collected during 1 week. METHODS We collected spot urine samples over 7… CONTINUE READING

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