Variability in the renin/aldosterone profile under random and standardized sampling conditions in primary aldosteronism.

@article{Tanabe2003VariabilityIT,
  title={Variability in the renin/aldosterone profile under random and standardized sampling conditions in primary aldosteronism.},
  author={Akiyo Tanabe and Mitsuhide Naruse and Sachiko Takagi and Ken Tsuchiya and Toshihiro Imaki and Kazue Takano},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2003},
  volume={88 6},
  pages={2489-94}
}
An increased plasma aldosterone concentration (PAC) with decreased plasma renin activity (PRA) is the abnormal endocrine finding in primary aldosteronism (PA). However, it remains unknown whether this profile is universal when blood samples are obtained in a random manner. We retrospectively evaluated the renin/aldosterone profile in 71 patients with PA due to unilateral adrenal adenoma. Blood samples were obtained randomly at an out-patient clinic and under standardized conditions during… CONTINUE READING
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