Variability in the pharmacokinetics and pharmacodynamics of low dose aspirin in healthy male volunteers.

@article{Benedek1995VariabilityIT,
  title={Variability in the pharmacokinetics and pharmacodynamics of low dose aspirin in healthy male volunteers.},
  author={Irma H. Benedek and Anjali S. Joshi and Henry J. Pieniaszek and Soas King and David M Kornhauser},
  journal={Journal of clinical pharmacology},
  year={1995},
  volume={35 12},
  pages={1181-6}
}
Data describing the pharmacokinetics and pharmacodynamics of low dose aspirin (acetylsalicylic acid; ASA) are limited. This single-center study was designed to determine the rate and extent of oral absorption of 80-mg ASA tablets in healthy, young male subjects and to assess the intra- and inter-subject variability of ASA pharmacokinetics and platelet aggregation effects. Ten subjects each received a single, open-label, oral 80-mg ASA dose on three separate days. Each dose was separated by a 2… CONTINUE READING