Variability in the Bioavailability of Phenytoin Capsules in Males and Females

Abstract

Purpose. To determine inter-lot and intra-subject variability in the bioavailability of the 100 mg extended phenytoin sodium capsules. In addition, to determine the effect of gender and menstrual cycle on phenytoin bioavailability. Methods. Three different lots of extended phenytoin sodium capsules were given to 12 healthy male and 12 healthy female… (More)
DOI: 10.1023/A:1011075502215

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