Variability in interval production is due to timing-dependent deficits in Huntington's disease.

@article{Rao2014VariabilityII,
  title={Variability in interval production is due to timing-dependent deficits in Huntington's disease.},
  author={A. K. Prasada Rao and Karen S. Marder and Jasim Uddin and Brian C. Rakitin},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2014},
  volume={29 12},
  pages={1516-22}
}
In Huntington's disease (HD), increased variability is seen in performance of motor tasks that require implicit control of timing. We examined whether timing variability was also evident in an explicit interval-timing task. Sixty subjects (21 controls, 19 manifest HD, and 20 pre-manifest HD) performed a single-interval production task with three target intervals (1.1 s, 2.2 s, 3.3 s). We analyzed accuracy (proportional error) and precision (standard deviation) across groups and intervals. No… CONTINUE READING