Variability in Hormone Concentrations and Self-Reported Menstrual Histories in Young Adolescents: Menarche as an Integral Part of a Developmental Process

  title={Variability in Hormone Concentrations and Self-Reported Menstrual Histories in Young Adolescents: Menarche as an Integral Part of a Developmental Process},
  author={Lorah D. Dorn and Editha D. Nottelmann and Elizabeth J. Susman and Gale Inoff-Germain and Gordon B. Cutler and George P. Chrousos},
  journal={Journal of Youth and Adolescence},
Menarche has been considered a marker for examining interindividual differences in biobehavioral development and for separating pubertal development into 2 stages. The purpose of this study was (1) to compare hormone concentrations in pre- and postmenarcheal girls to determine whether they fit a continuous or dichotomous model of pubertal development surrounding menarche; and (2) to address methodological issues of variability in self-reports of menstrual histories and reliability in reporting… 

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The present data support the view that girls with early menarche have a more profound decrease in the sensitivity of the hypothalamic‐pituitary unit to the negative feed‐back of circulating steroids.