Variability and lack of predictive ability of asthma end-points in clinical trials.

@article{Zhang2002VariabilityAL,
  title={Variability and lack of predictive ability of asthma end-points in clinical trials.},
  author={Ji Zhang and C Yu and Stephen T. Holgate and Theodore F. Reiss},
  journal={The European respiratory journal},
  year={2002},
  volume={20 5},
  pages={1102-9}
}
While a consensus definition of the clinical parameters important in asthma control exists, an adequate objective definition of a response to asthma treatment and parameters for prediction of that response remain undefined. Given that asthma is a complex biological disease and that different parameters may measure dissimilar aspects of the disease status, this study assessed the relationship among several end-points of asthma control, and attempted to select a combination of variables measured… CONTINUE READING

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