Varenicline: for smoking cessation.

@article{Rao2009VareniclineFS,
  title={Varenicline: for smoking cessation.},
  author={J. Rao and P. K. Shankar},
  journal={Kathmandu University medical journal},
  year={2009},
  volume={7 26},
  pages={
          162-4
        }
}
  • J. Rao, P. K. Shankar
  • Published 2009
  • Medicine
  • Kathmandu University medical journal
  • Varenicline, a partial agonist of alpha4beta2 nicotinic acetylcholine receptor (nAChR), is the most recently approved drug for smoking cessation. Despite the availability of effective treatments for smoking cessation, such as nicotine replacement therapy and Bupropion sustained-release, abstinence rates remain less than optimal. As a nAChR partial agonist, Varenicline attenuates the craving and withdrawal symptoms that occur with abstinence from nicotine and also reduces the rewarding effects… CONTINUE READING
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