Vardenafil increases penile rigidity and tumescence in men with erectile dysfunction after a single oral dose.

@article{Stark2001VardenafilIP,
  title={Vardenafil increases penile rigidity and tumescence in men with erectile dysfunction after a single oral dose.},
  author={Simone Stark and Richard Sachse and Tim Liedl and Johannes Hensen and Gabriele Rohde and Georg Wensing and Rolf Horstmann and Karl Michael Schrott},
  journal={European urology},
  year={2001},
  volume={40 2},
  pages={181-8; discussion 189-90}
}
OBJECTIVES To evaluate the effect of two doses of vardenafil hydrochloride on penile rigidity and tumescence while determining the pharmacokinetics. METHODS Twenty-one patients with erectile dysfunction completed three oral single-dose regimens (placebo, 20 and 40 mg vardenafil) in a randomized, placebo-controlled, 3-way cross-over study. Penile rigidity and tumescence were measured at the base and tip with a Rigiscan for up to 2 h after dosing. The period included three 20-min repeated… CONTINUE READING