Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice

  title={Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice},
  author={T. Lefever and Julie A Marusich and B. Thomas and Daniel G. Barrus and N. Peiper and Richard C. Kevin and J. Wiley},
  journal={Substance Abuse: Research and Treatment},
  • T. Lefever, Julie A Marusich, +4 authors J. Wiley
  • Published 2017
  • Medicine
  • Substance Abuse: Research and Treatment
  • Smoking is the most common route of administration for cannabis; however, vaping cannabis extracts and synthetic cannabinoids (“fake marijuana”) in electronic cigarette devices has become increasingly popular. Yet, most animal models used to investigate biological mechanisms underlying cannabis use employ injection as the route of administration. This study evaluated a novel e-cigarette device that delivers aerosolized cannabinoids to mice. The effects of aerosolized and injected synthetic… CONTINUE READING
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