Vaping-Associated Acute Lung Injury: A Case Series.

@article{Triantafyllou2019VapingAssociatedAL,
  title={Vaping-Associated Acute Lung Injury: A Case Series.},
  author={Georgios A. Triantafyllou and Perry J Tiberio and Richard H Zou and Phillip E. Lamberty and Michael J. Lynch and John W. Kreit and Mark T. Gladwin and Alison Morris and Jared Chiarchiaro},
  journal={American journal of respiratory and critical care medicine},
  year={2019}
}
View on PubMed
doi.org
72 Citations
Highly Influential Citations
4
Background Citations
19
Methods Citations
1
Results Citations
3

72 Citations

Pulmonary toxicity and inflammatory response of e-cigarettes containing medium-chain triglyceride oil and vitamin E acetate: Implications in the pathogenesis of EVALI but independent of SARS-COV-2 COVID-19 related proteins
TLDR
Overall, this study demonstrates acute exposure to specific e-cig cartridges induces in vitro cytotoxicity, barrier dysfunction, and inflammation and in vivo mouse exposure induces acute inflammation with elevated pro-inflammatory markers in the pathogenesis of EVALI.
E-Zigaretten – Funktionsweise, Inhaltsstoffe und die Vaping-assoziierte akute Lungenschädigung
TLDR
Basierend auf zumeist US-amerikanischen Studien zum Thema soll ein allgemeiner Uberblick uber die prinzipielle Funktionsweise of E-Zigaretten, die Inhaltsstoffe der verdampften Flussigkeiten (E-Liquids) sowie die damit verbundenen Inhalationsrisiken gegeben werden.
[E-Cigarettes - Operating Principle, Ingredients, and Associated Acute Lung Injury].
TLDR
An overview of recent, mainly US literature on EVALI is provided, including the case definition, epidemiology, clinical presentation, typical disease progression, as well as potential triggers.
How harmless are E-cigarettes? Effects in the pulmonary system.
TLDR
It is the opinion that E-cigarettes can no longer be defined as harmless, as it is evident that a large proportion of E-cigarette users are never-smokers, meaning they cannot only be considered from a harm reduction perspective.
E-cigarette or Vaping product use Associated Lung Injury (EVALI) in a 15 year old female patient – case report
TLDR
It is of interest to report the cases in which EVALI is identified to raise awareness about this emerging new-age disease due to the novelty of the condition and its heterogeneous presentation.
E-vape and E-Cigarettes-Associated Lung Injury (EVALI) in the COVID-19 Pandemic: A Diagnostic Dilemma and Therapeutic Challenge
TLDR
This case report demonstrates the dilemma in diagnosing EVALI in a 19-year-old female during the COVID-19 pandemic.
E-cigarettes and youth: an unresolved Public Health concern
TLDR
This review tried to summarize the latest updated information found in the literature, concentrating mainly in the variety of adverse effects of e-cigarette use and its contribution for recent and future health concerns.
Adolescent e‐cigarette or vaping product use‐associated lung injury: A case series and review of the literature
Adolescent e‐cigarette or vaping product use‐associated lung injury (EVALI) has increased in prevalence, and while cases describing various pulmonary manifestations have been reported, reports on the…
Smoky Diagnosis: Importance of Patient History in Vaping Associated Lung Injury
TLDR
A case of a young patient presenting with hypoxic respiratory failure due to EVALI, in which diagnosis was delayed due to incomplete patient history is presented.
Hemoptysis induced by vaping.
...
...

References

SHOWING 1-8 OF 8 REFERENCES
Imaging of Vaping-Associated Lung Disease.
Imaging of Vaping-Associated Lung Disease A sampling of imaging findings in patients with lung disease associated with electronic cigarette use is provided.
Lung injury from inhaling butane hash oil mimics pneumonia
Cinnamaldehyde in flavored e-cigarette liquids temporarily suppresses bronchial epithelial cell ciliary motility by dysregulation of mitochondrial function.
TLDR
Data indicate that cinnamaldehyde rapidly disrupts mitochondrial function, inhibits bioenergetic processes, and reduces ATP levels, which correlates with impaired CBF.
Prevalence and Distribution of E-Cigarette Use Among U.S. Adults: Behavioral Risk Factor Surveillance System, 2016
TLDR
The most up-to-date national and state-level prevalence of current e-cigarette use among U.S. adults was determined using the largest and most extensive dynamic health survey, the 2016 Behavioral Risk Factor Surveillance System (BRFSS), to help inform the work of researchers, public health officials, and regulatory authorities seeking to understand current trends in e-cigarettes.
Pro-inflammatory effects of e-cigarette vapour condensate on human alveolar macrophages
TLDR
ECVC is significantly more toxic to AMs than non-vaped ECL and inhibition of phagocytosis suggests users may suffer from impaired bacterial clearance, and is cautioned against the widely held opinion that e-cigarettes are safe.
"Tree-in-Bloom": Severe Acute Lung Injury Induced by Vaping Cannabis Oil.
In vitro particle size distributions in electronic and conventional cigarette aerosols suggest comparable deposition patterns.
TLDR
Nicotine delivery may depend on vaping technique, particle evolution, and cloud effects, and predicted 10% arterial and 15% venous delivery may describe bystander exposure better than vapers exposure.
Chronic E‐Cigarette Exposure Alters the Human Bronchial Epithelial Proteome
TLDR
Chronic vaping exerts marked biological effects on the lung and these effects may in part be mediated by the PG/VG base, likely not harmless and may have clinical implications for the development of chronic lung disease.