Vanilloids in pancreatic cancer: potential for chemotherapy and pain management.

@article{Hartel2006VanilloidsIP,
  title={Vanilloids in pancreatic cancer: potential for chemotherapy and pain management.},
  author={Mark Hartel and Francesco Fabio di Mola and Francesco Selvaggi and G Mascetta and Moritz N. Wente and Klaus Felix and Nathalia A. Giese and Ursula G. Hinz and Pierluigi di Sebastiano and Markus W. B{\"u}chler and Helmut Friess},
  journal={Gut},
  year={2006},
  volume={55 4},
  pages={
          519-28
        }
}
BACKGROUND Success of chemotherapy and alleviation of pain are frequently less than optimal in pancreatic cancer patients, leading to increasing interest in new pharmacological substances, such as vanilloids. Our study addressed the question of whether vanilloids influence pancreatic cancer cell growth, and if vanilloids could be used for pain treatment via the vanilloid 1 receptor (VR1) in pancreatic cancer patients. METHODS In vitro, the effect of resiniferatoxin (vanilloid analogue) on… CONTINUE READING

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