Vanillin inhibits PqsR-mediated virulence in Pseudomonas aeruginosa.

@article{Mok2020VanillinIP,
  title={Vanillin inhibits PqsR-mediated virulence in Pseudomonas aeruginosa.},
  author={Nicholas E. Mok and Shepherd Yuen Chan and Sylvia Yang Liu and Song Lin Chua},
  journal={Food \& function},
  year={2020},
  volume={11 7},
  pages={
          6496-6508
        }
}
Reduced efficacy of antibiotics in bacterial diseases is a global concern in clinical settings. Development of anti-virulence compounds which disarm bacterial virulence is an attractive therapeutic agent for complementary antibiotics usage. One potential target for anti-virulence compounds is quorum sensing (QS), the intercellular communication system in most pathogens, such as Pseudomonas aeruginosa. QS inhibitors (QSIs) can inhibit QS effectively, attenuate QS-mediated virulence, and improve… 
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