Vancomycin prevents polytetrafluoroethylene graft infections in pediatric patients receiving chronic hemodialysis.

Abstract

Polytetrafluoroethylene (PTFE) grafts have been a useful addition to the pediatric hemodialysis vascular access armamentarium. In this study, 17 pediatric patients underwent 331 total months of hemodialysis via PTFE grafts. There was a statistically significant (P less than .025) decrease in the incidence of graft infections in 12 patients (235 patient-months) while receiving prophylactic parenteral vancomycin compared with 9 patients (96 patient-months) while receiving no vancomycin (0% v 44%). Vancomycin side effects were uncommon and mild. Vancomycin is a safe and effective agent for the prevention of PTFE graft infections in pediatric patients receiving chronic hemodialysis.

Cite this paper

@article{Fivush1985VancomycinPP, title={Vancomycin prevents polytetrafluoroethylene graft infections in pediatric patients receiving chronic hemodialysis.}, author={Barbara A. Fivush and Glenn H. Bock and Philip C. Guzzetta and Jos{\'e} R. Salcedo and Edward J. Ruley}, journal={American journal of kidney diseases : the official journal of the National Kidney Foundation}, year={1985}, volume={5 2}, pages={120-3} }