Vancomycin nephrotoxicity: myths and facts.

  title={Vancomycin nephrotoxicity: myths and facts.},
  author={Ankur Gupta and Mohan Biyani and Ambar Khaira},
  journal={The Netherlands journal of medicine},
  volume={69 9},
Vancomycin is a key antibiotic in the management of severe Gram-positive infections. Recent emergence of methicillin-resistant staphylococcal strains with reduced susceptibility to vancomycin has prompted internists to administer high-dose treatment to achieve trough levels of 15 to 20 mg/l. Such high doses might be causative in nephrotoxicity. The risk further increases in patients who are critically ill and are on vasopressor support and/or concomitant nephrotoxic agents, with baseline… CONTINUE READING