Vancomycin adsorption to Bacillus subtilis cell walls.

@article{Best1965VancomycinAT,
  title={Vancomycin adsorption to Bacillus subtilis cell walls.},
  author={Gary K. Best and Norman N. Durham},
  journal={Archives of biochemistry and biophysics},
  year={1965},
  volume={111 3},
  pages={
          685-91
        }
}
Abstract Vancomycin adsorbs to whole cells and isolated cell walls of Bacillus subtilis W23. This binding occurs very rapidly and is not affected by temperature between 4 ° and 37 °C. The initial binding of vancomycin to cell walls occurs by ionic bonding between basic groups on the antibiotic and acid groups on the wall. Magnesium and other cations compete with vancomycin for binding sites. The effect of esterification of cell walls with diazomethane on the infrared spectrum of the walls and… CONTINUE READING

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