Vancomycin MICs of the resistant mutants of S. aureus ATCC43300 vary based on the susceptibility test methods used

Abstract

Clinical failures with vancomycin against meticillin-resistant Staphylococcus aureus (MRSA) infections have challenged vancomycin’s standing as a first-line antimicrobial for these infections. Conventional MIC tests were not predictive of the in vivo therapeutic effect of vancomycin. Thus, we tested the susceptibility for the resistant mutants in the mutant… (More)
DOI: 10.1038/ja.2012.18

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