Vanadium biochemistry: The unknown role of vanadium-containing cells in ascidians (sea squirts)

  title={Vanadium biochemistry: The unknown role of vanadium-containing cells in ascidians (sea squirts)},
  author={M. J. Smith},
  • M. Smith
  • Published 15 May 1989
  • Chemistry
  • Experientia
This article reviews several new developments in vanadium biochemistry, as elucidated from studies of ascidians. A hypothesis correlating ascidian blood cell function to anaerobiosis, via two prominent redox constituents, namely vanadium(III) and the tunichromes, a family of metal ion complexing/reducing hydroquinonoid peptides, is presented. 
Mendeleev’s Periodic Table and Marine Biomolecules
The mini-review highlights the involvement of some elements of Mendeleev Periodic Table into marine biogenic compounds and these elements participation in the marine organisms’ metabolism. Some
Structure and function of vanadium compounds in living organisms
The function of vanadium, while still illusive in ascidians and toadstools, begins to be understood in vanadium-enzyme interaction.
Presence of 3,4-dihydroxyphenylalanine-containing peptides in hemocytes of the ascidian,Halocynthia roretzi
Five 3,4-dihydroxyphenylalanine (DOPA)-containing peptides have been isolated from hemocytes of the ascidian,Halocynthia roretzi. Three of them were composed of DOPA, proline, phenylalanine,
Chemistry of Marine Natural Substances: Originality, Diversity, Distribution
The article contains sections titled: General Introduction Distribution of Nitrogenous and Non-Nitrogenous Secondary Metabolites Distribution of Secondary Metabolites by Chemical Class
In vivo incorporation of14C-phenylalanine into ascidian tunichrome
Ascidia ceratodes exposed to14C-phenylalanine in the surrounding seawater incorporates the radiolabel into newly biosynthesized tunichrome molecules, which can function as a precursor in the biosynthesis of Tunichrome.
From sea squirts to squirrelfish: facultative trace element hyperaccumulation in animals.
Examples of animal hyperaccumulation of the elements arsenic, copper, iron, titanium, vanadium and zinc are examined, describing mechanisms by which accumulation occurs and, where possible, hypothesizing functional roles.
Ascidians (Tunicates)–2
The article contains sections titled Metabolites of Polyclinidae, Long-Chain Sulfated Alkanes and Terpenes of Sidnyum turbinatum, and Nitrogenous Derivatives of Styelidae.
Oxovanadium complexes with multidentate ligands
Vanadium has ability to coordinate with multidentate ligands in different geometries to produce variety of complexes. Usually the reactions are carried out by refluxing the methanolic solution of
Compounds of Mo, V and W in biochemistry and their biomedical activity.


A new cyclic peptide, ascidiacyclamide, isolated from ascidian
A new cytotoxic cyclic peptide, ascidiacyclamide, has been isolated from ascidian and its structure has been elucidated by n.m.r. spectroscopy.
Vanadium and other metals in ascidians
  • D. B. Carlisle
  • Medicine
    Proceedings of the Royal Society of London. Series B. Biological Sciences
  • 1968
It is now more than half a century since Henze (1911) first demonstrated the presence of the metal vanadium in the blood of ascidians. He showed that the vanadium was organically bound (although to
Ultrastructural localization of vanadium in the blood cells of Ascidiacea
Results show a clear accumulation of vanadium on the membrane and in the granules of vacuoles of amebocytes, signet ring cell, compartment cell and traces of metal in the ‘vanadophores’ of vanadocytes.
Didemnins and tunichlorin: novel natural products from the marine tunicate Trididemnum solidum.
Didemnins A, B, and C, cyclic depsipeptides previously reported by our laboratory from the Caribbean tunicate Trididemnum solidum, have now been synthesized and, in the process, their structures have
Siderophores of bacteria and fungi.
  • J. Neilands
  • Biology, Chemistry
    Microbiological sciences
  • 1984
Of the various siderophore systems present in E. coli, the enterobactin and aerobactIn genes, encoded on the chromosome and pColV respectively, have been the most intensively studied to date as regards their molecular genetics.
Autonomous fluorescence of ascidian blood cells with special reference to identification of vanadocytes
A tunichrome that has been suggested to be involved in the accumulation of vanadium ions in ascidian blood cells produces an autonomous fluorescence upon excitation with blue-violet light. However,
Enterobactin, an iron transport compound from Salmonella typhimurium.