Vanadium(V) and -(IV) complexes of anionic polysaccharides: Controlled release pharmaceutical formulations and models of vanadium biotransformation products.

@article{Kremer2015VanadiumVA,
  title={Vanadium(V) and -(IV) complexes of anionic polysaccharides: Controlled release pharmaceutical formulations and models of vanadium biotransformation products.},
  author={Lauren E Kremer and A. Ian McLeod and Jade B Aitken and Aviva Levina and Peter A Lay},
  journal={Journal of inorganic biochemistry},
  year={2015},
  volume={147},
  pages={227-34}
}
Uncontrolled reactions in biological media are a main obstacle for clinical translation of V-based anti-diabetic or anti-cancer pro-drugs. We investigated the use of controlled-release pharmaceutical formulations to ameliorate this issue with a series of V(V) and (IV) complexes of anionic polysaccharides. Carboxymethyl cellulose, xanthan gum, or alginic… CONTINUE READING