Vanadate effects on ocular pressure, (Na+, K+)ATPase and adenylate cyclase in rabbit eyes.

@article{Mittag1984VanadateEO,
  title={Vanadate effects on ocular pressure, (Na+, K+)ATPase and adenylate cyclase in rabbit eyes.},
  author={Thomas Wesley Mittag and Janet B Serle and Steven M. Podos and Louis Cohen and F Liebowitz},
  journal={Investigative ophthalmology & visual science},
  year={1984},
  volume={25 11},
  pages={1335-8}
}
Topical administration of 50 microliter of 1% Na3VO4 caused a significant fall in intraocular pressure (IOP) in the rabbit eye at 90 min. Assay of ATPase of the iris and ciliary body in vitro at 90 min posttreatment showed no differences between control and treated (Na+, K+)ATPase, ouabain sensitive ATPase or vanadate sensitive ATPase. Accumulation of 48V… CONTINUE READING