Vamana Couples Fat Signaling to the Hippo Pathway.

Abstract

The protocadherins Dachsous and Fat initiate a signaling pathway that controls growth and planar cell polarity by regulating the membrane localization of the atypical myosin Dachs. How Dachs is regulated by Fat signaling has remained unclear. Here we identify the vamana gene as playing a crucial role in regulating membrane localization of Dachs and in… (More)
DOI: 10.1016/j.devcel.2016.09.017

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