Valve interstitial cell shape modulates cell contractility independent of cell phenotype.

@article{Tandon2016ValveIC,
  title={Valve interstitial cell shape modulates cell contractility independent of cell phenotype.},
  author={Ishita Tandon and Atefeh Razavi and Prashanth Ravishankar and Addison M Walker and Nasya M. Sturdivant and Ngoc Thien Lam and Jeffrey C. Wolchok and Kartik Balachandran},
  journal={Journal of biomechanics},
  year={2016},
  volume={49 14},
  pages={3289-3297}
}
Valve interstitial cells are dispersed throughout the heart valve and play an important role in maintaining its integrity, function, and phenotype. While prior studies have detailed the role of external mechanical and biological factors in the function of the interstitial cell, the role of cell shape in regulating contractile function, in the context of… CONTINUE READING