Value of water mazes for assessing spatial and egocentric learning and memory in rodent basic research and regulatory studies.

@article{Vorhees2014ValueOW,
  title={Value of water mazes for assessing spatial and egocentric learning and memory in rodent basic research and regulatory studies.},
  author={Charles V Vorhees and Michael T Williams},
  journal={Neurotoxicology and teratology},
  year={2014},
  volume={45},
  pages={75-90}
}
Maneuvering safely through the environment is central to survival of all animals. The ability to do this depends on learning and remembering locations. This capacity is encoded in the brain by two systems: one using cues outside the organism (distal cues), allocentric navigation, and one using self-movement, internal cues and sometimes proximal cues, egocentric navigation. Allocentric navigation involves the hippocampus, entorhinal cortex, and surrounding structures (e.g., subiculum); in humans… CONTINUE READING