Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases.

@article{Colletta2005ValueOT,
  title={Value of two noninvasive methods to detect progression of fibrosis among HCV carriers with normal aminotransferases.},
  author={Cosimo Colletta and Carlo Smirne and C. Fabris and Pierluigi Toniutto and Rachele Rapetti and Rosalba Minisini and Mario Pirisi},
  journal={Hepatology},
  year={2005},
  volume={42 4},
  pages={838-45}
}
The course of hepatitis C virus (HCV) infection carriers with normal/near-normal aminotransferases (NALT) is usually mild; however, in a few, fibrosis progression occurs. We aimed to verify whether monitoring by liver biopsy might be replaced by noninvasive methods and to identify factors associated with fibrosis progression in patients with persistently normal alanine aminotransferases. We studied 40 untreated HCV-RNA-positive subjects (22 male; median age, 44 years), who underwent two liver… CONTINUE READING