Value of the micropig model of menopause in the assessment of benefits and risks of postmenopausal therapies for cardiovascular and reproductive tissues.

Abstract

OBJECTIVE To extend the comparative database demonstrating the cardioprotective benefits of estrogen therapy to an additional relevant species and to assess the usefulness of this model for studies designed to assess benefits and risks of postmenopausal therapies. DESIGN Prospective, randomized, controlled periclinical trial. SETTING Medical university… (More)

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