Value of serum human epidermal growth factor receptor 2 (HER2)/neu testing for early prediction of response to HER2/neu-directed therapies is still an open one and deserves further study in large prospective trials.

Abstract

TO THE EDITOR: The recent article by Lennon et al draws a very different conclusion about the value of the serum human epidermal growth factor receptor 2 (HER2)/neu test then did our previously published work by Ali et al. We wish to make the following observations. The number of patients who were HER2/neu tissue positive and treated with first-line… (More)
DOI: 10.1200/JCO.2009.23.4674

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