Value of sentinel node status as a prognostic factor in melanoma: prospective observational study.

  title={Value of sentinel node status as a prognostic factor in melanoma: prospective observational study.},
  author={Stephen Kettlewell and Colin Moyes and Caroline A. Bray and David A Soutar and Alan Mackay and Dominique Byrne and Taimur Shoaib and Barun Majumder and R. E. Mackie},
  volume={332 7555},
OBJECTIVE To establish the prognostic value of knowledge of sentinel node status in melanoma. DESIGN Single centre prospective observational study, with sentinel nodes identified by lymphoscintigraphy, gamma probe, and intraoperative blue dye and examined by both conventional histopathology and immunopathology. SETTING Specialist surgical service in west of Scotland. PARTICIPANTS 482 patients with melanoma who consented to sentinel node biopsy in 1996-2003. MAIN OUTCOME MEASURE Time to… CONTINUE READING


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