Value of measuring muscle performance to assess changes in lean mass with testosterone and growth hormone supplementation

@article{Schroeder2011ValueOM,
  title={Value of measuring muscle performance to assess changes in lean mass with testosterone and growth hormone supplementation},
  author={E. Todd Schroeder and Jiaxiu He and Kevin E Yarasheski and Ellen F. Binder and Carmen Castaneda-Sceppa and Shalender Bhasin and Christina M Dieli-Conwright and Miwa Kawakubo and Ronenn Roubenoff and Stanley Paul Azen and Fred R. Sattler},
  journal={European Journal of Applied Physiology},
  year={2011},
  volume={112},
  pages={1123-1131}
}
We hypothesized that treatment with testosterone (T) and recombinant human growth hormone (rhGH) would increase lean mass (LM) and muscle strength proportionally and an in a linear manner over 16 weeks. This was a multicenter, randomized, controlled, double-masked investigation of T and rhGH supplementation in older (71 ± 4 years) community-dwelling men. Participants received transdermal T at either 5 or 10 g/day as well as rhGH at 0, 3.0 or 5.0 μg/kg/day for 16 weeks. Body composition was… CONTINUE READING