Value of hydroxyproline measurements in the assessment of late radiation enteropathy.

@article{Jensen1986ValueOH,
  title={Value of hydroxyproline measurements in the assessment of late radiation enteropathy.},
  author={M Hauer Jensen and T. Sauer and Knut Sletten and Jon B Reitan and K. Nygaard},
  journal={Acta radiologica. Oncology},
  year={1986},
  volume={25 2},
  pages={137-42}
}
In female Wistar rats roentgen irradiation of a 10 cm long temporarily exteriorized mid small intestinal segment was performed. Hydroxyproline, proline, aspartic acid and threonine were measured in intestinal samples 2 to 44 weeks after single or fractionated irradiation, and compared with a histopathologic radiation injury score in order to determine their value as assays of late radiation enteropathy. Two to 4 weeks after irradiation there was good correlation between the histopathologic… CONTINUE READING