Valsartan in the Treatment of Heart Attack Survivors

@article{Jugdutt2006ValsartanIT,
  title={Valsartan in the Treatment of Heart Attack Survivors},
  author={Bodh I. Jugdutt},
  journal={Vascular Health and Risk Management},
  year={2006},
  volume={2},
  pages={125 - 138}
}
Survivors of myocardial infarction (MI) are at high risk of disability and death. This is due to infarct-related complications such as heart failure, cardiac remodeling with progressive ventricular dilation, dysfunction, and hypertrophy, and arrhythmias including ventricular and atrial fibrillation. Angiotensin (Ang) II, the major effector molecule of the renin-angiotensin-aldosterone system (RAAS) is a major contributor to these complications. RAAS inhibition, with angiotensin-converting… CONTINUE READING

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View 1 Excerpt
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References

Publications referenced by this paper.
Showing 1-10 of 127 references

Limitation of excessive

F Zannad, F Alla, B Dousset
2000
View 4 Excerpts
Highly Influenced

A clinical trial

L Kober, C Torp-Pedersen, JE Carlsen
Clin Exp Pharmacol Physiol, • 1995
View 5 Excerpts
Highly Influenced

Effect of Valsartan on hospitalization: results from Val-HeFT.

Journal of cardiac failure • 2003
View 1 Excerpt
Highly Influenced

Val-HeFT Investigators (Valsartan Heart Failure Trial)

AP Maggioni, I Anand, SO Gottlieb
J Am Coll Cardiol, • 2002
View 1 Excerpt
Highly Influenced

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