Valpha and Vbeta public repertoires are highly conserved in terminal deoxynucleotidyl transferase-deficient mice.

@article{Fazilleau2005ValphaAV,
  title={Valpha and Vbeta public repertoires are highly conserved in terminal deoxynucleotidyl transferase-deficient mice.},
  author={Nicolas Fazilleau and Jean-Pierre Cabaniols and Fabrice Lema{\^i}tre and Iris Motta and P. Kourilsky and Jean M. Kanellopoulos},
  journal={Journal of immunology},
  year={2005},
  volume={174 1},
  pages={345-55}
}
T cell repertoires observed in response to immunodominant and subdominant peptides include private, i.e., specific for each individual, as well as public, i.e., common to all mice or humans of the same MHC haplotype, Valpha-Jalpha and Vbeta-Dbeta-Jbeta rearrangements. To measure the impact of N-region diversity on public repertoires, we have characterized… CONTINUE READING