• Biology, Medicine
• Published in
  Journal of steroid…
  1987
• DOI:10.1016/0022-4731(87)91061-2

Validity of the calculation of non-sex hormone-binding globulin-bound estradiol from total testosterone, total estradiol and sex hormone-binding globulin concentrations in human serum.

@article{Belgorosky1987ValidityOT,
  title={Validity of the calculation of non-sex hormone-binding globulin-bound estradiol from total testosterone, total estradiol and sex hormone-binding globulin concentrations in human serum.},
  author={Alicia Belgorosky and Mar{\'i}a Eugenia Reyes Escobar and Marco Aurelio Rivarola},
  journal={Journal of steroid biochemistry},
  year={1987},
  volume={28 4},
  pages={
          429-32
        }
}

• Alicia Belgorosky, María Eugenia Reyes Escobar, Marco Aurelio Rivarola

Recent evidences indicate that biologically available serum testosterone (T) and estradiol (E2) include not only the free fractions but also most of the albumin-bound fractions. These two serum T or E2 fractions constitute most of non-sex hormone-binding globulin (SHBG)-bound T or E2, respectively. It has been reported that the estimation of serum non-SHBG-bound T gives identical results when it is assayed experimentally or when it is calculated by a formula derived from the law of mass action… CONTINUE READING

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