Validity of self-reports of caffeine use.

  title={Validity of self-reports of caffeine use.},
  author={John S. Kennedy and Lisa L. von Moltke and Jerold S. Harmatz and Nina Engelhardt and David J Greenblatt},
  journal={Journal of clinical pharmacology},
  volume={31 7},
The relationship between self-reports of caffeine ingestion on two occasions and measured plasma concentrations of caffeine and its major metabolites was examined. A subject population [25 men and 25 women, age 20-45 years (mean: 28.7 yr)] that was enrolled in a benzodiazepine pharmacokinetic study underwent general medical screening on two occasions, each including detailed caffeine histories. Before beginning their scheduled study, plasma samples were obtained and evaluated by HPLC for… CONTINUE READING