Validity of multiple-time regression analysis in measurement of tritiated and iodinated leptin crossing the blood-brain barrier: meaningful controls.

Abstract

Multiple-time regression analysis has been used to study the influx of radiolabeled peptides and polypeptides across the blood-brain barrier (BBB). This study used both tritiated and iodinated leptin to clarify several issues associated with these measurements. Recombinant murine leptin was radiolabeled with 3H by derivatization or with 125I by the iodobead… (More)

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@article{Kastin2001ValidityOM, title={Validity of multiple-time regression analysis in measurement of tritiated and iodinated leptin crossing the blood-brain barrier: meaningful controls.}, author={Abba J. Kastin and Victoria L Akerstrom and Wei Pan}, journal={Peptides}, year={2001}, volume={22 12}, pages={2127-36} }