Validation studies for models projecting the risk of invasive and total breast cancer incidence.

  title={Validation studies for models projecting the risk of invasive and total breast cancer incidence.},
  author={J. P. Costantino and Mitchell H. Gail and David Y Pee and Sibyl Anderson and Carol K. Redmond and Jacques Benichou and H Samuel Wieand},
  journal={Journal of the National Cancer Institute},
  volume={91 18},
BACKGROUND In 1989, Gail and colleagues developed a model for estimating the risk of breast cancer in women participating in a program of annual mammographic screening (designated herein as model 1). A modification of this model to project the absolute risk of developing only invasive breast cancer is referred to herein as model 2. We assessed the validity of both models by employing data from women enrolled in the Breast Cancer Prevention Trial. METHODS We used data from 5969 white women who… CONTINUE READING
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