Validation of tractography: Comparison with manganese tracing

  title={Validation of tractography: Comparison with manganese tracing},
  author={Thomas R. Kn{\"o}sche and Alfred Anwander and Matthew Liptrot and Tim B. Dyrby},
  booktitle={Human brain mapping},
In this study, we used invasive tracing to evaluate white matter tractography methods based on ex vivo diffusion-weighted magnetic resonance imaging (dwMRI) data. A representative selection of tractography methods were compared to manganese tracing on a voxel-wise basis, and a more qualitative assessment examined whether, and to what extent, certain fiber tracts and gray matter targets were reached. While the voxel-wise agreement was very limited, qualitative assessment revealed that… CONTINUE READING
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