Validation of the sterilization procedure of allogeneic avital bone transplants using peracetic acid-ethanol.

@article{Pruss2001ValidationOT,
  title={Validation of the sterilization procedure of allogeneic avital bone transplants using peracetic acid-ethanol.},
  author={Axel Pruss and Britta Baumann and Michael Seibold and Moujahed Kao and Kathrin Tintelnot and R{\"u}diger von Versen and Hartmut Radtke and Thomas Doerner and Georg Pauli and Ulf Berthold G{\"o}bel},
  journal={Biologicals : journal of the International Association of Biological Standardization},
  year={2001},
  volume={29 2},
  pages={59-66}
}
Different procedures are available to inactivate bacteria and fungi, including their spores, as well as viruses in human bone transplants. The most efficient methods are considered to be gamma irradiation and thermal inactivation as well as chemical sterilization methods like the peracetic acid-ethanol treatment (PES). Following national and international standards or draft standards, the antimicrobial effectiveness of this procedure was evaluated. Due to the standardizable size as well as the… CONTINUE READING

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