Validation of the predictive capabilities of the Sbrc-G in vitro assay for estimating arsenic relative bioavailability in contaminated soils.

@article{Juhasz2014ValidationOT,
  title={Validation of the predictive capabilities of the Sbrc-G in vitro assay for estimating arsenic relative bioavailability in contaminated soils.},
  author={Albert L. Juhasz and Paul J Herde and Carina Herde and Jennifer Boland and Euan Smith},
  journal={Environmental science & technology},
  year={2014},
  volume={48 21},
  pages={12962-9}
}
A number of bioaccessibility methodologies have the potential to act as surrogate measures of arsenic (As) relative bioavailability (RBA), however, validation of the in vivo-in vitro relationship is yet to be established. Validation is important for human health risk assessment in order to ensure robust models for predicting As RBA for refining exposure via incidental soil ingestion. In this study, 13 As-contaminated soils were assessed for As RBA (in vivo swine model) and As bioaccessibility… CONTINUE READING

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