Validation of the association of genetic variants on chromosome 9p21 and 1q41 with myocardial infarction in a Japanese population.

@article{Hiura2008ValidationOT,
  title={Validation of the association of genetic variants on chromosome 9p21 and 1q41 with myocardial infarction in a Japanese population.},
  author={Yumiko Hiura and Yasue Fukushima and Miyuki Yuno and Hiromi Sawamura and Yoshihiro Kokubo and Tomonori Okamura and Hitonobu Tomoike and Yoichi Goto and Hiroshi Nonogi and Rie Takahashi and Naoharu Iwai},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2008},
  volume={72 8},
  pages={1213-7}
}
BACKGROUND Recent large-scale genome-wide association studies have identified several loci associated with the risk of coronary artery disease (CAD). The aim of the present study was to examine whether the previously reported CAD-associated single-nucleotide polymorphisms (SNPs) confer susceptibility to myocardial infarction (MI) in a study population of 2,475 controls and 589 cases of MI. The effect of the CAD-associated SNPs on cardiovascular risk factors in the control group was also… CONTINUE READING

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