Validation of the Oxford classification of IgA nephropathy.

  title={Validation of the Oxford classification of IgA nephropathy.},
  author={Andrew M. Herzenberg and Agnes B. Fogo and Heather Naomi Reich and St{\'e}phan Troyanov and N{\"u}ket Bavbek and Alfonso Eirin Massat and Tracy Earl Hunley and Michelle A. Hladunewich and Bruce A Julian and Fernando C Fervenza and Daniel C. Cattran},
  journal={Kidney international},
  volume={80 3},
The Oxford classification of IgA nephropathy (IgAN) identified four pathological elements that were of prognostic value and additive to known clinical and laboratory variables in predicting patient outcome. These features are segmental glomerulosclerosis/adhesion, mesangial hypercellularity, endocapillary proliferation, and tubular atrophy/interstitial fibrosis. Here, we tested the Oxford results using an independent cohort of 187 adults and children with IgAN from 4 centers in North America by… CONTINUE READING
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